In addition to the retina, post-translational regulation of Hes6 may occur elsewhere, given that Hes6 plays roles in late embryogenesis, myogenesis [195,196,197], and postnatal development [198,199], and its overexpression is linked to gliomas and breast and prostate cancer [200,201,202]. The gene discussed is HES6; the disease is Familial prostate cancer.