Using the NZM2410/J SLE mouse model, we also demonstrated that intramuscular administration of the EBV-dUTPase protein significantly enhanced glomerulonephritis characterized by interstitial/tubular cellular infiltrates, increased IgG complex formation and C3 deposition in glomeruli as well as a strong induction of IL-17 in glomeruli and tubules [32]. This evidence concerns the gene IL17A and systemic lupus erythematosus.