The six other known cryptic exons (CE1–5, CE9) appear in AR transcripts in prostate cancer cells via alterative splicing or due to genomic rearrangements within the AR gene, generating approximately 20 variant AR transcripts (e.g., AR-V1 to AR-V18, AR8, and AR23) [7,9,10,11,12,13]. This evidence concerns the gene AR and Familial prostate cancer.