PTPN11 and large cell medulloblastoma: Statistical correlations were established between p-STAT3 nuclear translocation and the level of SOCS3 (R = 0.333; p = 0.047) or PIAS3 expression (R = −0.494; p = 0.002) but not p-SHP2 down-regulation (R = 0.02; p > 0.05) in the large-cell medulloblastomas.