PIAS3 and medulloblastoma: The current study aims to address these issues using medulloblastoma microarrays to profile SHP2, SOCS3 and PIAS3 expression patterns in medulloblastoma tissues and resveratrol-sensitive medulloblastoma cell lines to elucidate the impact(s) of resveratrol in SHP2, SOCS3 and PIAS3 expression when exerting its inhibitory effect on STAT3 signaling and cell proliferation.