GLP-1’s most well-characterized biological function is to potentiate glucose-dependent insulin secretion, although it has other effects, such as suppressing appetite and glucagon secretion, which make the GLP-1 receptor (GLP-1R) an attractive target in the treatment of type 2 diabetes mellitus [1,2,3,4,5]. The gene discussed is GLP1R; the disease is type 2 diabetes mellitus.