MST1 and cancer: Heterozygous and homozygous deletion of YAP dramatically suppresses tumorigenesis in LKB1-, Mob1-, and NF2-deficient liver [50, 63, 120], Mst1/2-deficient phenotypes in the small intestine and colon [121], and the early progression to pancreatic ductal adenocarcinoma in a Kras (G12D) cancer model [122].