In particular, we found that the metabolism of AXL-FL is sensitive to treatment with DAPT in NSCLC cells, which is in agreement with a recent observation that AXL can be degraded in H292 NSCLC cells by presenilin, the catalytic subunit of γ-secretase, as suggested on a single Western blot by the fact that AXL was sensitive to treatment with a γ-secretase inhibitor (43). Here, AXL is linked to non-small cell lung carcinoma.