CXCL1 and cancer: As for cancer cell migration, senescent HPMCs stimulated this process via CXCL1 and TGF-β1 (in A2780 cultures); CXCL1, CXCL8, and fibronectin in OVCAR-3 cells; and CXCL8 and IL-6 in SKOV-3 cells (Figures 3j–l).