In addition, the data revealed that expressional levels of ST3GAL6 (12.34-folds) and ST8SIA4 (5.71-folds) were upregulated in the highly metastatic breast cancer cell line MDA-MB-231 compared with the slightly metastatic breast cancer cell line MCF-7 (Figures 2a and e). Here, ST8SIA4 is linked to breast cancer.