ST8SIA5 and breast carcinoma: In comparison with MCF-10A cells, the aggressive breast cancer cell line MDA-MB-231 showed an increased number of differentially expressed genes including ST6GALNAC5 (7.33-folds), ST8SIA4 (14.81-folds) and ST8SIA5 (3.11-folds) (Figures 2c and e).