HTRA1 and age-related macular degeneration: In fact, in this study, none of the major risk variants for AMD e.g., HtrA serine peptidase 1 (HTRA1)/age-related maculopathy susceptibility 2 (ARMS2) or complement factor H (CFH), were significant in the non-white European populations after correction for multiple testing, but this was likely due to the small sample size used in this study [52].