The authors evaluated 139 PCa patients with pT3 or positive margins after RP who received postoperative XRT (both adjuvant and salvage) and found that the addition of Decipher GC improved the AUC of a clinical model (i.e., Stephenson model) from 0.70 to 0.78 and from 0.70 to 0.80 as a predictor of BCR and distant metastasis, respectively. Here, BCR is linked to posterior cortical atrophy.