When we focused on the prognostic value of low-expressed genes in primary AML cohort, low expression of G3BP1 and DDX41 correlated with a shorter survival (P < .001 and P = .04, Figure 4C), an effect that was not seen in CSNK1A1 cases (Figure 4C). The gene discussed is G3BP1; the disease is acute myeloid leukemia.