AFP and hepatocellular carcinoma: The Cox proportional hazards model also showed that the Clinical stage III/IV (HR, 4.607; 95% CI, 2.345–9.049), the HCV-related HCC with cirrhosis subgroup (HR, 3.009; 95% CI, 1.325–6.835), > 20 ng/mL AFP (HR, 2.192; 95% CI, 1.197–4.016) and the high risk group of MPM-BC (cut-off value > 0.45) (HR, 3.624; 95% CI, 1.424–9.223) were associated with high mortality rates (Figure 6B).