We further analyzed the various clinico-pathological factors like age, gender, AFP, vascular invasion, tumor size, the clinical stage, the viral cirrhosis group and the MPM-BC by using the multivariate Cox proportional hazard model and found that the clinical stage (P < 0.0001), MPM-BC (P = 0.0069), the viral cirrhosis group (P = 0.0085) and AFP (P = 0.011) were statistically significant for overall survival (Table 3). Here, AFP is linked to neoplasm.