Mutant Kras induction of eukaryotic translation initiation factor 5A, which plays a critical role in PDAC tumor growth (Fujimura et al, 2014), facilitates elevation of ROCK1 and ROCK2 protein levels in pancreatic cancer cells (Fujimura et al, 2015), indicating that there are also post‐transcriptional mechanisms that may contribute to increased ROCK expression in PDAC. This evidence concerns the gene EIF5A and familial pancreatic carcinoma.