Another research by Ondrusova et al. in a cohort of 879 TC survivors showed that in 823 patients with unilateral TC, a testosterone deficiency was found in 19.5% of cases, with an increased LH in 19.1%, and bone damage (osteopenia and/or osteoporosis) in 50.6% of cases [33]. The gene discussed is PLOD1; the disease is Osteopenia.