In multivariate Cox regression analysis, high count of intratumoral CD68+ Mφ [HR: 2.70 (1.00–7.31); p=0.050] and high expression of FOXP3 in cancer cells [HR: 0.29 (0.09–0.91); p=0.034] were independent prognostic factors for overall survival. The gene discussed is FOXP3; the disease is cancer.