SNCA and Parkinson disease: Next, we wanted to analyze exposed epitopes of in vivo deposited alpha-synuclein aggregates by performing immunohistochemistry with the antibodies on formalin-fixed and paraffin-embedded tissue sections of (Thy-1)-h[A30P] alpha-synuclein transgenic mouse brain and sections from the substantia nigra of PD, PDD, and DLB patients.