AKT1 and herpes simplex infectious disease: Using KegArray, it was found that the five most significant abundant KO pathways were for: Metabolic Pathways (107 members), PI3K-Akt Signaling Pathway (43 members), Pathways in Cancer (39 members), Human T-Lymphotropic virus-1 Infection (36 members), and Herpes Simplex Infection (36 members).