Expression of both pank1 and pank2 is maximal in the ookinete stage in P. berghei [56] supporting the notion that CoA biosynthesis is important during transmission of P. berghei. As a number of inhibitors of this pathway are currently being investigated for asexual inhibition of the malaria parasite [65,66,69–71], these studies should be extended to assess the transmission-blocking capacity of these inhibitors. This evidence concerns the gene PANK2 and malaria.