Both primary cell lines from MCL cases and MCL cell lines (including Jeko-1, Mino, Rec-1, Hbl-2, and Granta-519) were used to generate disease in immunodeficient NOD.Cg-Prkdcscid Il2rgtm1Wgl/Szj mice or NOD.SCID mice (40–42). This evidence concerns the gene CTSG and mantle cell lymphoma.