ZNF644, Zinc-Finger Protein 644, encodes a zinc-finger transcription factor, interacts with G9a to regulate gene expression during neurogenesis.26 In addition, mutations in ZNF644 have been associated with myopia.27 UBE2D4, Ubiquitin Conjugating Enzyme E2 D4, encodes a protein that is involved in the p53 and ubiquitination pathways.28 However, based on predicted functional impact and biological relevance, ZNF644 and UBE2D4 are unlikely to contribute to the phenotype. This evidence concerns the gene UBE2D4 and myopia.