TP53 and myopia: ZNF644, Zinc-Finger Protein 644, encodes a zinc-finger transcription factor, interacts with G9a to regulate gene expression during neurogenesis.26 In addition, mutations in ZNF644 have been associated with myopia.27 UBE2D4, Ubiquitin Conjugating Enzyme E2 D4, encodes a protein that is involved in the p53 and ubiquitination pathways.28 However, based on predicted functional impact and biological relevance, ZNF644 and UBE2D4 are unlikely to contribute to the phenotype.