This decay pattern was first used empirically in 2007–2008 to fine map the TRAF1 region in rheumatoid arthritis (Schrodi et al., 2007a) and the IL23R region in psoriasis (Garcia et al., 2008) and has, in an analogous form, subsequently been used in other applications (Farh et al., 2015). This evidence concerns the gene TRAF1 and rheumatoid arthritis.