NAMPT and cancer: In fact, this method could permit the detection of new inhibitors of two enzymes, which are currently targets in cancer therapy (Cerna et al., 2012; Duarte-Pereira et al., 2016) – the human NAMPT (EC 2.4.2.12) and the nicotinate phosphoribosyltransferase (NaPRT) (EC 6.3.4.21), which use NAM and NA as substrates to convert them into NMN and nicotinic acid mononucleotide (NaMN), respectively.