In fact, this method could permit the detection of new inhibitors of two enzymes, which are currently targets in cancer therapy (Cerna et al., 2012; Duarte-Pereira et al., 2016) – the human NAMPT (EC 2.4.2.12) and the nicotinate phosphoribosyltransferase (NaPRT) (EC 6.3.4.21), which use NAM and NA as substrates to convert them into NMN and nicotinic acid mononucleotide (NaMN), respectively. This evidence concerns the gene NAPRT and cancer.