Instead, in this study we tested the feasibility to reduce the frequency of MB lesions by forcing the preneoplastic granule neuron precursor cells (pGCPs) to migrate out of the lesions at the surface of the cerebellum and differentiate, withdrawing from the tumor program, by means of an intracerebellar treatment with the chemokine Cxcl3. The gene discussed is CXCL3; the disease is neoplasm.