Such findings are not without precedent in the adult brain: flow cytometry studies have displayed co-expression of CD206 and the pro-inflammatory marker major histocompatibility complex class II (MHCII) in the intact CNS (Li et al., 2014), and CD206+/FcγRII/III+cells have been detected in a mouse model of traumatic brain injury (Bedi et al., 2013). The gene discussed is MRC1; the disease is brain injury.