Microglia express galectin-3 after ischemic injury in adult and neonatal brain (Walther et al., 2000; Doverhag et al., 2010) and in the adult brain galectin-3 is associated with protective IGF-1-expressing microglia after stroke (Lalancette-Hébert et al., 2007). The gene discussed is LGALS3; the disease is Stroke.