Biobanks of such patient samples are an invaluable source to researchers, and cells are often processed, banked, and used as defined cell populations, such as CD34+ and CD34+CD38− sorted cells, with CD34+ enrichment being used as a bare minimum to deplete the mature granulated cells that are numerous in CML and, when present, cause technical issues on degranulation during freeze–thaw. The gene discussed is CD34; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.