Furthermore, CRC-triggered CCID formation was inhibited by Y27632 in CT5.3 (Fig. 4c) and CAF3 (Fig. 4d) and by the RHO inhibitor rhosin (Fig. 4e, f) in a dose-dependent manner, which inhibited MLC2 phosphorylation (Supplementary Fig. S4) as well. The gene discussed is RHO; the disease is colorectal carcinoma.