TNF and rheumatoid arthritis: Patients with RA (n = 25, 18 female and 7 male; mean age ± SD 57.4 ± 11.7 years; mean disease duration ± SD 10.6 ± 9.2 years) with active disease (mean DAS28 ± SD 5.72 ± 0.84) were followed longitudinally during the initial 12 weeks of treatment with anti-TNF (18 patients were treated with etanercept and 7 patients with adalimumab).