Of these 20 studies, 13 evaluated multifocality, 11 evaluated TNM stage, 17 reported on extrathyroidal extension (ETE), 7 evaluated vascular invasion, 19 assessed lymph node metastases (LNM), 10 reported on distant metastases (DM), 4 assessed BRAF mutation, 7 reported disease-specific survival, and 4 evaluated overall survival. This evidence concerns the gene BRAF and metastatic malignant neoplasm in the lymph nodes.