However, Ghossein and Livolsi found that TCV is overrepresented in fluorodeoxyglucose positron-emission tomogram (FDG-PET)-positive thyroid carcinomas that are refractory to RAI therapy, which may due to a high prevalence of BRAF somatic mutations in patients with TCV [35]. The gene discussed is BRAF; the disease is thyroid gland carcinoma.