CD4 and neoplasm: Conversely, we could show that cDCs sorted from tdLNs of LLC-OVA tumour-bearing mice could stimulate OVA-specific CD8+ and CD4+ T-cell responses, indicative for in vivo migration of antigen-loaded cDCs from the tumour to the tdLNs, in line with the high CCR7 expression of these cells and as recently shown in other models44.