CD4 and neoplasm: Interestingly, cDC2 vaccination led to a reduced LLC-OVA, but not B16-OVA, tumour growth paralleled by an increased infiltration of RORγt+ CD4+ T cells, a reduction of monocytic and granulocytic MDSCs and a reprogramming of TAMs from a protumoral M2-like MHC-IIlow to an antitumoral M1-like MHC-IIhigh phenotype.