The expansion of CD33+CD11b+HLA-DR−/low cells was due to increase in the granulocytic CD15+ subset; high-grade CRC patients had significantly elevated levels of GMCs than HDs (high-grade: 86.0 ± 2.2 vs. HDs: 67.1 ± 2.7; Figure 4C) and low-grade CRC patients (low-grade: 73.2 ± 3.2; Figure 4C). The gene discussed is ITGAM; the disease is colorectal carcinoma.