CRP and infection: In the two groups, the median leukocyte counts, value of C- reactive protein (CRP), and erythrocyte sedimentation rate (ESR) were abnormally increased within 1 week after the first-stage surgical treatment, and then gradually returned to normal at 2 months postoperatively, except for the persistent or recurrent infection, laboratory examination showed no nephrotoxic or hepatotoxic effects in each group.