Poor prognostic features were found in two other patients: low expression of PAX8, FHIT, CASP10, CHD2, with high expression of CHD11, FUS, and MTA1 in a patient with Ewing sarcoma [36], and gain of 1q and loss of 6q and overexpression of TNC, CALB1, PLAG1, ALDH1L1, and RELN in a patient with ependymoma [37]. The gene discussed is RELN; the disease is Ewing sarcoma.