The main finding of this meta-analysis is that most of the included studies indicate that PCT can be a simple and very useful biomarker for the early identification of sepsis in burn patients, when used in combination with relevant clinical examination and other biomarkers available (e.g. leukocytosis, C-reactive protein, MR-pro-adrenomedullin) [18,49–52]. This evidence concerns the gene CRP and Sepsis.