The CCAAT/enhancer-binding proteins α and β (C/EBPα and β) are reported to be downstream factors of TRIB2.24, 25 To investigate the effects of Smad3-related miRNAs on C/EBPα and β expression, lung adenocarcinoma cells were treated with miR-140 and miR-206. The gene discussed is SMAD3; the disease is lung adenocarcinoma.