AKT1 and polycystic ovary syndrome: The functional enrichment analysis based on data from the Kyoto Encyclopedia of Genes and Genomes (KEGG) revealed that differentially expressed genes in PCOS oocytes were mainly involved in the PI3K-Akt signaling pathway, gap junction pathway, calcium signaling pathway, and oocyte meiosis pathway (adjusted P value (Padj) < 0.05) (Fig. 3A), indicating those pathways may play important role in oocyte maturation.