CXCR3 and neoplasm: Brain homing has been shown to be enhanced by CXCL10, one of the CXCR3 ligands, secreted at the tumor environment (88), which can be promoted by injection of poly-ICLC (polyriboinosinic–polyribocytidylic acid stabilized with poly-l-lysine and carboxymethylcellulose), a TLR3 agonist.