Reduced airway hyperresponsiveness (assessed with whole-body barometric plethysmography)Reduced infiltrating cells (eosinophils and lymphocytes) in mice challenged by HDM or DM upon treatment with FIP-fveAt humoral level, increased IgG2a while decreased IgE in the serumReduced Th2 cytokines while increased Th1 and Treg cytokines in serum and BALFReduced inflammation and epithelial cell thickness (histological examination). This evidence concerns the gene IGHE and airway hyperresponsiveness.