Inhibition of tumor growth was 29.3% for treatment with RdB (754.3 ± 59.7 mm3), 50.2% with RdB/IL12 (531.7 ± 85.0 mm3), 37.3% with RdB/DCN (668.8 ± 80.1 mm3), and 78.2% with RdB/IL12/DCN (233.1 ± 36.4 mm3) compared with PBS-treated control tumors (P < 0.05 for RdB, P < 0.01 for RdB/DCN, P < 0.001 for RdB/IL12 and RdB/IL12/DCN versus PBS). The gene discussed is DCN; the disease is neoplasm.