Expression of the RAF1 binding partner MST2 and phosphorylation of MST1/2 were comparable in both genotypes; LATS1 was expressed at slightly higher levels in tumours of both genotypes, and no correlation could be established between RAF1 expression and the phosphorylation of LATS1 on T1079 in the hydrophobic motif. This evidence concerns the gene STK3 and neoplasm.