There was no statistically significant difference in the levels of E2 (p = 0.611), progesterone (p = 0.931), testosterone (p = 0.988), FSH (p = 0.323) and LH (p = 0.304) between premenopausal women with type 1(n = 59) and type 2 (n = 8) endometrial cancer. This evidence concerns the gene PLOD1 and endometrial cancer.