And, this leads to a general belief that WWOX sequesters prosurvival transcription factors in the cytoplasm to block cancer growth (Chang et al., 2001, 2003, 2005, 2007; Aqeilan et al., 2004; Aqeilan and Croce, 2007; Aldaz et al., 2014; Abu-Remaileh et al., 2015). The gene discussed is WWOX; the disease is cancer.