PRTN3 and microscopic polyangiitis: This includes Goodpasture disease (also known as anti-GBM disease) and a group of systemic vasculitides such as Wegener's disease, systemic lupus erythematosus, Churg-Strauss syndrome, microscopic polyangiitis, essential mixed cryoglobulinemia, and rheumatoid vasculitis where ANCA (either c-ANCA or p-ANCA) are usually detected [1].