On top of that, in an attempt to investigate the pathogenic role of IL-17A in osteoporosis, although more than 87 % of subjects did not have a remarkable levels of IL-17A in their blood (the low detection limit of the kit was less than 2.3 pg/ml) the number of osteoporotic subjects with detectable level of serum IL-17A was greater than the normal control (7.42(16.67%) versus 3.39(7.69%)). The gene discussed is IL17A; the disease is osteoporosis.