STAR and congenital adrenal hyperplasia: Furthermore, mutations in the human STAR gene (STARD1) were identified in patients with congenital lipoid adrenal hyperplasia (lipoid CAH), a disorder marked by a lack of adrenal and gonadal steroidogenesis due to the inability to move cholesterol into the mitochondria [(Lin et al., 1995; Bose et al., 2000); reviewed in (Miller, 2014)].