NFKB1 and Alzheimer disease: The underlying mechanisms rely in the decreased expression, upon chitosan/phospholipid/β-CD microspheres injection, of the protein kinase C-δ, whose overexpression in AD has been linked to NF-κB activation leading to central inflammation [129], and a reduced microglia activation in the rat hippocampus, both taking part in neurodegeneration and cognitive impairment in AD.