FBXW7 and viral infectious disease: In order to assess whether the altered RNAi efficiency after virus infection is due to an upregulation of the genes involved in the RNAi pathway, the expression levels of dcr-2, ago-2, ninaC, egghead and sid-1 were evaluated 24 h after IAPV infection (the moment the dsRNA is administered; virus injected compared to PBS injected; Figure 4A) and at the endpoint of the assay (72 h for IAPV and 96 h for CrPV; virus treatment compared to RNAi control; Figure 4B).