As indicated in Table 2, positive immunostaining of ELMO3 was significantly correlated with tumor size (p = 0.007), pathologic differentiation degree (p = 0.001), depth of invasion (p = 0.009), lymph node metastasis (p = 0.003), distant metastasis (p = 0.013) and TNM stage (p = 0.000). The gene discussed is ELMO3; the disease is neoplasm.