Clonal haematopoiesis in asymptomatic RUNX1 carriers under the age of 50 years was already reported 9 suggesting together with our results that the identification of clonal haematopoiesis before leukaemia development in FPD/AML patients could serve as a marker of pre‐leukaemic state. This evidence concerns the gene RUNX1 and acute myeloid leukemia.