KRT8 and infection: In addition, some keratins were also related to the function of epithelial cells, for example, keratin 8 and keratin 18 could guarantee rigidity and structure integrity of extracellular matrix of epithelial cells, affect intracellular transportation mechanism and signaling pathway, and might inhibit the apoptosis of epithelial cells [6–8]; keratin 8 could play a role in infection activity of transferable cells of epithelium [9].